Imakrebin Film-coated Tablets 100mg/400mg

Therapeutic class 治療性藥物
Anticancer 抗癌


The active substance is imatinibmesilate.

Each Imakrebin Film-coated Tablets 100mg contains 100 mg imatinib (as mesilate).

Each Imakrebin Film-coated Tablets 400mg contains 400 mg imatinib (as mesilate).

• The other ingredients are, microcrystalline cellulose, low substituted hydroxypropyl cellulose, povidone, crospovidone (Type A), silica colloidal anhydrous, magnesium stearate.

• The tablet coating is made of hypromellose, Polyethylene Glycol, talc, red iron oxide (E172), yellow iron oxide (E172).


Imakrebin is a medicine containing an active substance called imatinib. This

medicine works by inhibiting the growth of abnormal cells in the diseases listed

below. These include some types of cancer.


Imakrebin is a treatment for adults and children for:

-- Chronic myeloid leukaemia (CML).

-- Philadelphia chromosome positive acute lymphoblastic leukaemia (Phpositive ALL).

Imakrebin is also a treatment for adults for:

-- Myelodysplastic/myeloproliferative diseases (MDS/MPD).

-- Hypereosinophilic syndrome (HES) and/or chronic eosinophilic leukaemia (CEL).

-- Dermatofibrosarcoma protuberans (DFSP).

Imakrebin is NOT to be used for the treatment of GIST.



-- How much Imakrebin to take? 

Use in adults

Your doctor will tell you exactly how many tablets of Imakrebin to take.

Use in children and adolescents

The doctor will tell you how many tablets of Imakrebin to give to your child. The

amount of Imakrebin given will depend on your child’s condition, body weight and height. The total daily dose in children must not exceed 800 mg. The treatment can either be given to your child as a once-daily dose or alternatively the daily dose can be split into two administrations (half in the morning and half in the evening).


When and how to take Imakrebin?

-- Take Imakrebin with a meal. This will help protect you from stomach

problems when taking Imakrebin. 

-- Swallow the tablets whole with a large glass of water.

If you are unable to swallow the tablets, you can dissolve them in a glass of still

water or apple juice.


How long to take Imakrebin?

Keep taking Imakrebin every day for as long as your doctor tells you.

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